Axure vs Omnigraffle

Create Prototypes of Websites & Apps Without Coding. Axure RP gives you the wireframing, prototyping and specification tools needed to make informed design choices, persuade any skeptics, get your design built to spec... and maybe win a few fans along the way. Choose the Standard edition for prototyping or go Pro to add documentation and collaboration features.
OmniGraffle can help you make eye-popping graphic documents—quickly—by providing powerful styling tools, keeping lines connected to shapes even when they’re moved, and magically organizing diagrams with just one click. Create flow charts, diagrams, UI and UX interactions, and more. Whether you need a quick sketch or an epic technical figure, OmniGraffle and OmniGraffle Pro keep it gorgeously understandable.
Comparing Axure vs Omnigraffle is like comparing apples to oranges. Because your business is unique and nobody except you can decide, which is better for your company. But we can add some fun to your research and suggest some new comparison parameters.

Ok, now let's compare the UI. Looks like Axure has more user-friendly interface than Omnigraffle because it's bigger. At least on our screenshots

To compare the popularity of the solutions we counted how many alternatives people search for each of them on the Internet. And it turns out that Omnigraffle is more popular than Axure